Journal: Methods (San Diego, Calif.)

Article Title: Quantifying Transcription Factor Binding Dynamics at the Single-molecule Level in Live Cells

doi: 10.1016/j.ymeth.2017.03.014

Figure Lengend Snippet: (A) Performance based on the Jaccard Index of TrackRecord compared to the various methods described in, and using the simulated, medium density receptor data from Chenouard, et al [43] at several signal-to-noise values. (B) Extracted residence times from the same data as shown in (A) with a signal-to-noise value of 4 for Method 11 from Chenouard, et al [43], and TrackRecord. Although Method 11 performs better at tracking than TrackRecord based on the Jaccard Index in this scenario, TrackRecord is able to capture a wider range of residence time distributions than Method 11.

Article Snippet: 3.3 Data analysis Tracking was performed with the custom software TrackRecord [ 42 ] in MATLAB (The MathWorks, Inc., Natick, MA).

Techniques:

Journal: Molecular cell

Article Title: An intrinsically disordered region-mediated confinement state contributes to the dynamics and function of transcription factors

doi: 10.1016/j.molcel.2021.01.013

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: Single-molecule tracking analysis We used the custom-made software TrackRecord ( Mazza et al., 2013 ) in MATLAB (The MathWorks, Inc., Natick, MA).

Techniques: Recombinant, Electron Microscopy, Sample Prep, Magnetic Beads, Sequencing, Generated, Imaging, Stable Transfection, Software